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Article

Genetic Regulation of the Growth Plate

1 Jan 2012

Abstract excerpt

The epiphyseal growth plate consists of a layer of cartilage present only during the growth period and vanishes soon after puberty in long bones. It is divided to three well-defined zones, from epiphyses; resting, proliferative, and hypertrophic zones. Chondrocyte proliferation and differentiation and subsequent bone formation in this cartilage are controlled by various endocrine, autocrine, and paracrine factors...

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PMID: 22654844
DOI: 10.3389/fendo.2011.00113

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