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Article

Bone has a sexually dimorphic response to aromatase deficiency.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Mar 2000

Oz O K, Zerwekh J E, Fisher C, Graves K, Nanu L, Millsaps R, Simpson E R

Abstract excerpt

Aromatase synthesizes estrogen from androgen precursors. To better understand the role of estrogen in skeletal metabolism and growth, we have assessed long bone growth and histomorphometry in aromatase-deficient (ArKO) mice. The age range for the animals was 5-7 months. At this age mice have already achieved peak bone density but continue slow bone growth. Femur length, an index of long bone growth, showed...

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Source

Identifiers

PMID: 10750565
DOI: 10.1359/jbmr.2000.15.3.507

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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