Article
[Localization of p53(301-393) mutant and its effect on mitosis].
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences - 1 Jul 2007
Xu Yi-yi, Lan Jian-ping, Zhu Yuan-yuan
Abstract excerpt
OBJECTIVE: To observe the localization of p53(301-393)(residues 301-393) in p53 positive/negative cells and its effect on cell mitosis. METHODS: The protein expression of p53-GFP and p53(301-393)-GFP was checked by immunoblotting after transfection. Immunofluorescence staining was performed to detect the localization of wide type and mutant in Hela cells (p53 positive) and H1299 cells (p53 negative). The cell...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
