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[Inhibitory effect of p53 with deletion of c-terminal 356 - 393 amino acids on malignant phenotype of human lung cancer cell line].

Zhonghua zhong liu za zhi [Chinese journal of oncology] - 1 Nov 2003

Wang Hui, Li Jin-zhao, Lai Bai-tang, Yang Xue-hui, Zhang Chun-yan, Yue Wen-tao, Zhan Xiu-ping

Abstract excerpt

OBJECTIVE: To study the effect of extraneous p53 gene with deletion of c-terminal 356 - 393 amino acids on inhibition of malignant phenotype of human lung cancer cell line. METHODS: Recombinant plasmid pEGFP-p53 (del) with codon deletion of c-terminal 37 amino acids from 393 to 356 region and pEGFP-p53 (wild type) were constructed. The human lung cancer cell line 801D served as a receipt cell had p53 deletion and...

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PMID: 14690553

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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