Article
[Important role of Ser 219 phosphorylation of TRF1 in regulation of cell cycle].
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences - 1 Jul 2007
Xu Yi-yi, Lan Jian-ping, Zhu Yuan-yuan
Abstract excerpt
OBJECTIVE: To investigate the role of Ser 219 phosphorylation of TRF1 (telomere repeat binding factor 1) in regulation of cell cycle. METHODS: The mimicking phosphorylation mutant (TRF1S219D-GFP) and the non-phosphorylatable mutant (TRF1S219A-GFP) were constructed; the mutant genes and corresponding proteins were checked by sequencing and Western blot, respectively. Immunofluorescence staining was performed to...
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