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Article

Glutathione S-transferases pi 1, alpha 1 and M3 genetic polymorphisms and the risk of hepatocellular carcinoma in humans.

Pharmacogenomics - 1 Aug 2007

Ladero José M, Martínez Carmen, Fernández Juana M, Martín Felipe, García-Martín Elena, Ropero Paloma, Villegas Ana, Díaz-Rubio Manuel, Agúndez José A G

Abstract excerpt

INTRODUCTION: Glutathione S-transferases pi1, alpha1 and micro3 are members of an enzymatic superfamily involved in the conjugation and detoxification of carcinogens. Polymorphisms affecting the genes encoding these enzymes may modify their ability to neutralize carcinogens. Our aim was to investigate whether these polymorphisms affect the risk of developing hepatocellular carcinoma in humans. METHODS: A total of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17716224
DOI: 10.2217/14622416.8.8.895

Genes

GSTP1
GSTA1
GSTM3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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