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Article

Glutathione S-transferase M1 and T1 genetic polymorphisms are not related to the risk of hepatocellular carcinoma: a study in the Spanish population.

European journal of cancer (Oxford, England : 1990) - 1 Jan 2006

Ladero José M, Martínez Carmen, García-Martín Elena, Ropero Paloma, Briceño Olga, Villegas Ana, Díaz-Rubio Manuel, Agúndez José A G

Abstract excerpt

Glutathione S-transferases constitute a superfamily of enzymes that catalyse the inactivating conjugation of endogenous and environmental substrates involved in the pathogenesis of hepatocellular carcinoma (HCC) and glutathione. Genes encoding either glutathione S-transferase Mu-1 or Theta-1 (GSTM1 and GSTT1, respectively) isoforms are polymorphic. Homozygotes for the mutated inactive alleles of each gene are...

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Source

Identifiers

PMID: 16314088
DOI: 10.1016/j.ejca.2005.08.033

Genes

GSTM1
GSTT1
DHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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