Article
Influence of glutathione-S-transferase theta (GSTT1) and micro (GSTM1) gene polymorphisms on the susceptibility of hepatocellular carcinoma in Taiwan.
Journal of surgical oncology - 15 Sept 2010
Kao Chia-Chun, Chen Mu-Kuan, Kuo Wu-Hsien, Chen Tzy-Yen, Su Shih-Chi, Hsieh Yi-Hsien, Liu Chuen-Lan, Chou Ming-Chih, Tsai Hsiu-Ting, Yang Shun-Fa
Abstract excerpt
BACKGROUND AND OBJECTIVES: Hepatocellular carcinoma (HCC) is one of the most frequent malignant neoplasms worldwide and is the second leading cause of cancer death in Taiwan. Genetic polymorphism has been reported as a factor for increased susceptibility of HCC. Glutathione-S-transferases theta (GSTT1) and micro (GSTM1) play essential roles in detoxification of ingested xenobiotics and modulation of the...
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