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Article

Glutathione S-Transferase P1 (GSTP1) gene polymorphism increases age-related susceptibility to hepatocellular carcinoma.

BMC medical genetics - 24 Mar 2010

Chen Yao-Li, Tseng Hsin-Shun, Kuo Wu-Hsien, Yang Shun-Fa, Chen Dar-Ren, Tsai Hsiu-Ting

Abstract excerpt

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most frequent malignant neoplasms in the world. Genetic polymorphism has been reported to be a factor increasing the risk of HCC. Phase II enzymes such as glutathione s-transferases (GSTP1, GSTA1) play important roles in protecting cells against damage induced by carcinogens. The aim of this study was to estimate the relationship of the GSTP1 and GSTA1 gene...

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Source

Open in PubMed Open full text

Identifiers

PMID: 20331903
DOI: 10.1186/1471-2350-11-46
PMCID: PMC2851593

Genes

GSTP1
GSTA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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