Article
Susceptibility genes: GSTM1 and GSTM3 as genetic risk factors in bladder cancer.
Cytogenetics and cell genetics - 1 Jan 2000
Schnakenberg E, Breuer R, Werdin R, Dreikorn K, Schloot W
Abstract excerpt
Glutathione S-transferase (GST, E.C. 2.5.1.18) comprises a family of isoenzymes that play a key role in the detoxification of such exogenous substrates as xenobiotics, environmental substances, and carcinogenic compounds. At least five mammalian GST gene families have been identified to be polymorphic, and mutations or deletions of these genes contribute to the predisposition for several diseases, including...
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