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Article

Relation between GSTP1 polymorphism and oxidative stress in patients with hepatocellular carcinoma.

Journal of the Egyptian National Cancer Institute - 2 Oct 2020

Elofey Shaimaa Gamal Hassan, Shafik Nevine F, Radwan Noha Hassan, Mansour Osman Mohammed, Allam Rasha Mahmoud, Shouman Samia, AbdelGawad Iman Attia

Abstract excerpt

BACKGROUND: Glutathione can reduce the oxidative stress by converting the unstable to stable molecules and its status in hepatocellular carcinoma (HCC) is correlated with tumor growth and metastasis. Glutathione S-transferase Pi (GSTP1) is reported to detoxify the xenobiotic substrates by catalyzing their conjugation to reduced glutathione (GSH) and its over-expression was demonstrated in the early stages of HCC,...

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Source

Open in PubMed Open full text

Identifiers

PMID: 33006026
DOI: 10.1186/s43046-020-00049-x
PMCID: PMC13317083

Genes

GSTP1

Variants

rs1695

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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