Article
Polymorphism of the Pi class glutathione S-transferase in normal populations and cancer patients.
Pharmacogenetics - 1 Feb 1998
Harris M J, Coggan M, Langton L, Wilson S R, Board P G
Abstract excerpt
Deficiencies of the glutathione transferase isoenzymes GSTM1-1 and GSTT1-1 have been shown to be risk modifiers in a number of different cancers but there have been no similar studies with GSTP1-1, the only member of the Pi class of glutathione S-transferases expressed in humans. Over-expression...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Base Sequence
- Case-Control Studies
- Codon
- Colorectal Neoplasms
- DNA Primers
- Female
- Gene Frequency
- Genotype
- Glutathione S-Transferase pi
- Glutathione Transferase
- Humans
- Isoenzymes
- Linkage Disequilibrium
- Lung Neoplasms