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Article

Polymorphism of the Pi class glutathione S-transferase in normal populations and cancer patients.

Pharmacogenetics - 1 Feb 1998

Harris M J, Coggan M, Langton L, Wilson S R, Board P G

Abstract excerpt

Deficiencies of the glutathione transferase isoenzymes GSTM1-1 and GSTT1-1 have been shown to be risk modifiers in a number of different cancers but there have been no similar studies with GSTP1-1, the only member of the Pi class of glutathione S-transferases expressed in humans. Over-expression of GSTP1-1 in tumours suggests that it may be a significant factor in acquired resistance to certain anticancer drugs....

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Source

Identifiers

PMID: 9511178
DOI: 10.1097/00008571-199802000-00004

Genes

GSTP1
GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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