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Article

Polymorphisms of the glutathione S-transferase P1 gene and head and neck cancer susceptibility.

Head & neck - 1 Jan 2003

Oude Ophuis Michael B, Roelofs Hennie M J, van den Brandt Piet A, Peters Wilbert H M, Manni Johannes J

Abstract excerpt

BACKGROUND: Factors determining the individual susceptibility to head and neck squamous cell carcinoma (HNSCC) are still largely unknown. An imbalance between enzymes involved in the toxification and detoxification of (pre)-carcinogens closely related to HNSCC, which may appear during smoking and alcohol consumption, may play a role. Genetic polymorphisms in glutathione S-transferases (GSTs) often result in...

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Source

Identifiers

PMID: 12478542
DOI: 10.1002/hed.10182

Genes

GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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