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Article

Growth and drug resistance phenotypes resulting from cytomegalovirus DNA polymerase region III mutations observed in clinical specimens.

Antimicrobial agents and chemotherapy - 1 Nov 2007

Chou Sunwen, Marousek Gail I, Van Wechel Laura C, Li Shaobing, Weinberg Adriana

Abstract excerpt

Recombinant phenotyping of cytomegalovirus (CMV) pol region III mutations from clinical specimens showed that T813S and G841A each conferred foscarnet resistance and approximately threefold increased ganciclovir resistance; adding the UL97 mutation C592G increased ganciclovir resistance to approximately sixfold. Bacterial artificial chromosome CMV clones containing pol mutation L845P were nonviable unless...

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Source

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Identifiers

PMID: 17709468
DOI: 10.1128/AAC.00736-07
PMCID: PMC2151462

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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