Article
The biology of cytomegalovirus drug resistance.
Current opinion in infectious diseases - 1 Dec 2011
Hakki Morgan, Chou Sunwen
Abstract excerpt
PURPOSE OF REVIEW: This review assesses recently published data on cytomegalovirus (CMV) antiviral drug resistance. RECENT FINDINGS: Resistance is typically encountered after prolonged ganciclovir treatment for posttransplant primary CMV infection and is diagnosed by the detection of characteristic mutations in the viral UL97 kinase and UL54 DNA polymerase genes in clinical specimens. One of seven canonical UL97...
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