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Article

Phenotypic diversity of cytomegalovirus DNA polymerase gene variants observed after antiviral therapy.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Apr 2011

Chou Sunwen

Abstract excerpt

BACKGROUND: Cytomegalovirus UL54 DNA polymerase mutations observed in clinical specimens are of diagnostic significance if confirmed to affect antiviral drug susceptibility. OBJECTIVES: Validate an updated recombinant phenotyping method to determine the degree of drug resistance conferred by previously uncharacterized UL54 sequence variants, in comparison with known resistance-related mutations. STUDY DESIGN:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to DNA-Directed DNA Polymerase

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Source

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Identifiers

PMID: 21295516
DOI: 10.1016/j.jcv.2011.01.004
PMCID: PMC3059355

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