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Article

Phenotypic evaluation of previously uncharacterized cytomegalovirus DNA polymerase sequence variants detected in a valganciclovir treatment trial.

The Journal of infectious diseases - 15 Apr 2014

Chou Sunwen, Boivin Guy, Ives Jane, Elston Robert

Abstract excerpt

BACKGROUND: In a large randomized trial comparing oral valganciclovir and intravenous ganciclovir for treatment of cytomegalovirus disease in solid organ transplantation, confirmed genotypic drug resistance was uncommon (<5%), but definitive interpretation was limited by the detection of 110 uncharacterized UL54 viral DNA polymerase sequence variants. METHODS: Based on treatment history and genetic locus of the...

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Identifiers

PMID: 24273181
DOI: 10.1093/infdis/jit654
PMCID: PMC3969548

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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