Article
A conditional role of U2AF in splicing of introns with unconventional polypyrimidine tracts.
Molecular and cellular biology - 1 Oct 2007
Sridharan Vinod, Singh Ravinder
Abstract excerpt
Recognition of polypyrimidine (Py) tracts typically present between the branch point and the 3' splice site by the large subunit of the essential splicing factor U2AF is a key early step in pre-mRNA splicing. Diverse intronic sequence arrangements exist, however, including 3' splice sites lacking recognizable Py tracts, which raises the question of how general the requirement for U2AF is for various intron...
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