Article
Both the polypyrimidine tract and the 3' splice site function prior to the first step of splicing in fission yeast.
Nucleic acids research - 15 Nov 1997
Romfo C M, Wise J A
Abstract excerpt
While it is known that several trans -acting splicing factors are highly conserved between Schizosaccharomyces pombe and mammals, the roles of cis -acting signals have received comparatively little attention. In Saccharomyces cerevisiae, sequences downstream from the branch point are not required prior to the first transesterification reaction, whereas in mammals the polypyrimidine tract and, in some introns, the...
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