Article

Widespread separation of the polypyrimidine tract from 3’ AG by G tracts in association with alternative exons in metazoa and plants

2018-07-06

Abstract excerpt

<h4>Summary</h4> At the end of introns, the polypyrimidine tract (Py) is often close to the 3’ AG in a consensus (Y) 20 NC AG gt in humans. Interestingly, we have found that they could also be separated by purine-rich elements including G tracts in thousands of human genes. These regulatory elements between the Py and 3’AG (REPA) mainly regulate alternative 3’ splice sites (3’SS) and intron retention. Here we s...

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Literature Corpus work: b4c717b7-2ad5-5c7f-b03a-5afb01931597
DOI: 10.1101/363804

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