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Article

IFNGR1 gene promoter polymorphisms and susceptibility to cerebral malaria.

The Journal of infectious diseases - 1 Jun 2002

Koch Oliver, Awomoyi Agnes, Usen Stanley, Jallow Muminatou, Richardson Anna, Hull Jeremy, Pinder Margaret, Newport Melanie, Kwiatkowski Dominic

Abstract excerpt

Interferon (IFN)-gamma is a critical mediator of immunity to malaria. This study explored the relationship between polymorphisms in the promoter region of the gene encoding IFN-gamma receptor 1 (IFNGR1) and susceptibility to malaria in African children. Four polymorphisms were found in the region between -1400 and +100 nt of the translational start site by sequencing, and analysis of 562 nuclear families revealed...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12023780
DOI: 10.1086/340516

Genes

IFNGR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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