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Ifi202, an IFN-inducible candidate gene for lupus susceptibility in NZB/W F1 mice, is a positive regulator for NF-kappaB activation in dendritic cells.

International immunology - 1 Aug 2007

Yamauchi Moriyasu, Hashimoto Masayuki, Ichiyama Kenji, Yoshida Ryoko, Hanada Toshikatsu, Muta Tatsushi, Komune Shizuo, Kobayashi Takashi, Yoshimura Akihiko

Abstract excerpt

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the presence of autoantibodies and lupus nephritis. The [New Zealand black (NZB) x New Zealand white (NZW)]F1 (BWF1) mouse has been recognized as an important animal model of human SLE. The T(h)1-prone phenotype of BWF1 mice has been shown to contribute to the development of the lupus. However, the molecular basis for T(h)1 skewing in...

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PMID: 17702989
DOI: 10.1093/intimm/dxm054

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Ifi202, an IFN-inducible candidate gene for lupus susceptibility in NZB/W F1 mice, is a positive regulator for NF-kappaB activation in dendritic cells.PMID 17702989Read ↗

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