Article
Phenotypic and functional alterations of pDCs in lupus-prone mice.
Scientific reports - 16 Feb 2016
Zhou Zhenyuan, Ma Jianyang, Xiao Chunyuan, Han Xiao, Qiu Rong, Wang Yan, Zhou Yingying, Wu Li, Huang Xinfang, Shen Nan
Abstract excerpt
Plasmacytoid dendritic cells (pDCs) were considered to be the major IFNα source in systemic lupus erythematosus (SLE) but their phenotype and function in different disease status have not been well studied. To study the function and phenotype of pDCs in lupus-prone mice we used 7 strains of lupus-prone mice including NZB/W F1, NZB, NZW, NZM2410, B6.NZM(Sle1/2/3), MRL/lpr and BXSB/Mp mice and C57BL/6 as control...
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