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Article

Interferon-inducible Ifi200-family genes as modifiers of lupus susceptibility.

Immunology letters - 1 Sept 2012

Choubey Divaker

Abstract excerpt

Both genetic and environmental factors contribute to the development and progression of systemic lupus erythematosus (SLE), a complex autoimmune disease. The disease exhibits a strong gender bias and develops predominantly in females. Additionally, most SLE patients exhibit increased serum levels of interferon-α (IFN-α) and the "IFN signature". Studies using the mouse models of lupus have identified several lupus...

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Share to Autoimmunity
Share to Epistasis, Genetic
Share to Genes, Modifier

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunologic Factors

Share to Interferon Regulatory Factors

Share to Lupus Erythematosus, Systemic

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Identifiers

PMID: 22841963
DOI: 10.1016/j.imlet.2012.07.003
PMCID: PMC3425670

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