Article
Interleukin-6 induces expression of Ifi202, an interferon-inducible candidate gene for lupus susceptibility.
The Journal of biological chemistry - 16 Apr 2004
Pramanik Rocky, Jørgensen Trine N, Xin Hong, Kotzin Brian L, Choubey Divaker
Abstract excerpt
Systemic lupus erythematosus (SLE) is a prototype autoimmune disease. In human SLE patients, as well as in mouse models of SLE, the development of disease is associated with increased levels of pro-inflammatory cytokines, such as interleukin-6 (IL-6). However, IL-6 target genes contributing to the development of disease remain to be identified. Our previous studies of one mouse model of SLE identified an...
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