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Article

Repeat-associated siRNAs cause chromatin silencing of retrotransposons in the Drosophila melanogaster germline.

Nucleic acids research - 1 Jan 2007

Klenov Mikhail S, Lavrov Sergey A, Stolyarenko Anastasia D, Ryazansky Sergey S, Aravin Alexei A, Tuschl Thomas, Gvozdev Vladimir A

Abstract excerpt

Silencing of genomic repeats, including transposable elements, in Drosophila melanogaster is mediated by repeat-associated short interfering RNAs (rasiRNAs) interacting with proteins of the Piwi subfamily. rasiRNA-based silencing is thought to be mechanistically distinct from both the RNA interference and microRNA pathways. We show that the amount of rasiRNAs of a wide range of retroelements is drastically...

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PMID: 17702759
DOI: 10.1093/nar/gkm576
PMCID: PMC2018648

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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