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Article

Telomeric trans-silencing: an epigenetic repression combining RNA silencing and heterochromatin formation.

PLoS genetics - 1 Sept 2007

Josse Thibaut, Teysset Laure, Todeschini Anne-Laure, Sidor Clara M, Anxolabéhère Dominique, Ronsseray Stéphane

Abstract excerpt

The study of P-element repression in Drosophila melanogaster led to the discovery of the telomeric Trans-Silencing Effect (TSE), a repression mechanism by which a transposon or a transgene inserted in subtelomeric heterochromatin (Telomeric Associated Sequence or TAS) has the capacity to repress in trans in the female germline, a homologous transposon, or transgene located in euchromatin. TSE shows variegation...

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Source

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Identifiers

PMID: 17941712
DOI: 10.1371/journal.pgen.0030158
PMCID: PMC1976332

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Source receipt: pubmed, retrieved 7 Sept 2026.

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