Article

In the <i>Drosophila</i> germline H2Av and Arp6 suppress transposons by driving piRNA pathway expression

2026-05-21

Abstract excerpt

The spatiotemporal control of transcription and the maintenance of germline genome integrity depend on dynamic chromatin architecture. In Drosophila , the actin-related protein Arp6—a core subunit of the SWR1-like Domino chromatin remodeling complex—mediates the deposition of the histone variant H2Av. Previous studies have established H2Av as a key transcriptional regulator that modulates the +1 nucleosome barrie...

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Literature Corpus work: 2bd8a83b-f840-5a4f-96e5-66587b01321c
DOI: 10.64898/2026.05.19.726329

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