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Article

A distinct small RNA pathway silences selfish genetic elements in the germline.

Science (New York, N.Y.) - 21 Jul 2006

Vagin Vasily V, Sigova Alla, Li Chengjian, Seitz Hervé, Gvozdev Vladimir, Zamore Phillip D

Abstract excerpt

In the Drosophila germline, repeat-associated small interfering RNAs (rasiRNAs) ensure genomic stability by silencing endogenous selfish genetic elements such as retrotransposons and repetitive sequences. Whereas small interfering RNAs (siRNAs) derive from both the sense and antisense strands of their double-stranded RNA precursors, rasiRNAs arise mainly from the antisense strand. rasiRNA production appears not...

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PMID: 16809489
DOI: 10.1126/science.1129333

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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