Article
Key role of piRNAs in telomeric chromatin maintenance and telomere nuclear positioning in Drosophila germline
12 Jul 2018
Abstract excerpt
BACKGROUND: Telomeric small RNAs related to PIWI-interacting RNAs (piRNAs) have been described in various eukaryotes; however, their role in germline-specific telomere function remains poorly understood. Using a Drosophila model, we performed an in-depth study of the biogenesis of telomeric piRNAs and their function in telomere homeostasis in the germline. RESULTS: To fully characterize telomeric piRNA clusters,...