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Article

Isoprenylcysteine carboxy methylation is essential for development in Dictyostelium discoideum.

Molecular biology of the cell - 1 Oct 2007

Chen Ying, McQuade Kyle J, Guan Xiao-Juan, Thomason Peter A, Wert Michael S, Stock Jeffry B, Cox Edward C

Abstract excerpt

Members of the Ras superfamily of small GTPases and the heterotrimeric G protein gamma subunit are methylated on their carboxy-terminal cysteine residues by isoprenylcysteine methyltransferase. In Dictyostelium discoideum, small GTPase methylation occurs seconds after stimulation of starving cell...

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Identifiers

PMID: 17699599
DOI: 10.1091/mbc.e06-11-1006
PMCID: PMC1995708

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17699599-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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