Article
Assessment of development and chemotaxis in Dictyostelium discoideum mutants.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011
Artemenko Yulia, Swaney Kristen F, Devreotes Peter N
Abstract excerpt
Studies using the social amoeba Dictyostelium discoideum have greatly contributed to the current understanding of the signaling network that underlies chemotaxis. Since directed migration is essential for normal D. discoideum multicellular development, mutants with chemotactic impairments are likely to have abnormal developmental morphologies. We have used multicellular development as a readout in a screen of...
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