Article
The Drosophila homolog of the Exo84 exocyst subunit promotes apical epithelial identity.
Journal of cell science - 1 Sept 2007
Blankenship J Todd, Fuller Margaret T, Zallen Jennifer A
Abstract excerpt
The polarized architecture of epithelial tissues involves a dynamic balance between apical and basolateral membrane domains. Here we show that epithelial polarity in the Drosophila embryo requires the exocyst complex subunit homolog Exo84. Exo84 activity is essential for the apical localization of the Crumbs transmembrane protein, a key determinant of epithelial apical identity. Adherens junction proteins become...
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