crumbs encodes an EGF-like protein expressed on apical membranes of Drosophila epithelial cells and required for organization of epithelia.

doi:10.1016/0092-8674(90)90189-l

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Article

crumbs encodes an EGF-like protein expressed on apical membranes of Drosophila epithelial cells and required for organization of epithelia.

Cell - 1 Jun 1990

Tepass U, Theres C, Knust E

Abstract excerpt

We describe the molecular characterization of the Drosophila gene crumbs, which encodes an integral membrane protein with 30 EGF-like repeats in the extracellular part and exhibits a striking expression pattern. The protein is exclusively localized on the apical membranes of epithelial cells and...

Topics

Amino Acid Sequence
Animals
Base Sequence
Cloning, Molecular
Drosophila
Drosophila Proteins
Epidermal Growth Factor
Epithelium
Genes
Immunohistochemistry
Membrane Proteins
Molecular Sequence Data
Mutation
Nucleic Acid Hybridization

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