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Article

Essential function of Drosophila Sec6 in apical exocytosis of epithelial photoreceptor cells.

The Journal of cell biology - 23 May 2005

Beronja Slobodan, Laprise Patrick, Papoulas Ophelia, Pellikka Milena, Sisson John, Tepass Ulrich

Abstract excerpt

Polarized exocytosis plays a major role in development and cell differentiation but the mechanisms that target exocytosis to specific membrane domains in animal cells are still poorly understood. We characterized Drosophila Sec6, a component of the exocyst complex that is believed to tether secretory vesicles to specific plasma membrane sites. sec6 mutations cause cell lethality and disrupt plasma membrane...

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Identifiers

PMID: 15897260
DOI: 10.1083/jcb.200410081
PMCID: PMC2171699

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Essential function of Drosophila Sec6 in apical exocytosis of epithelial photoreceptor cells.PMID 15897260Read ↗

Identification of genes required for apical protein trafficking in Drosophila photoreceptor cellsSemantic proximity Read ↗

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Sec6 mutations and the Drosophila exocyst complex.Semantic proximity Read ↗

Exocyst Genes Are Essential for Recycling Membrane Proteins and Maintaining Slit Diaphragm in Drosophila NephrocytesSemantic proximity Read ↗

Rab6 Is Required for Multiple Apical Transport Pathways but Not the Basolateral Transport Pathway in Drosophila Photoreceptors.Semantic proximity Read ↗

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The Drosophila homolog of the Exo84 exocyst subunit promotes apical epithelial identity.Semantic proximity Read ↗

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