Article
Cadherin 99C regulates apical expansion and cell rearrangement during epithelial tube elongation.
Development (Cambridge, England) - 1 May 2014
Chung Seyeon, Andrew Deborah J
Abstract excerpt
Apical and basolateral determinants specify and maintain membrane domains in epithelia. Here, we identify new roles for two apical surface proteins - Cadherin 99C (Cad99C) and Stranded at Second (SAS) - in conferring apical character in Drosophila tubular epithelia. Cad99C, the Drosophila ortholog of human Usher protocadherin PCDH15, is expressed in several embryonic tubular epithelial structures. Through...
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