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Article

The claudin Megatrachea protein complex.

The Journal of biological chemistry - 26 Oct 2012

Jaspers Martin H J, Nolde Kai, Behr Matthias, Joo Seol-hee, Plessmann Uwe, Nikolov Miroslav, Urlaub Henning, Schuh Reinhard

Abstract excerpt

Claudins are integral transmembrane components of the tight junctions forming trans-epithelial barriers in many organs, such as the nervous system, lung, and epidermis. In Drosophila three claudins have been identified that are required for forming the tight junctions analogous structure, the septate junctions (SJs). The lack of claudins results in a disruption of SJ integrity leading to a breakdown of the...

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Identifiers

PMID: 22930751
DOI: 10.1074/jbc.M112.399410
PMCID: PMC3481279

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