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MICROSATELLITE ANALYSIS OF INDUCED SPUTUM DNA IN PATIENTS WITH LUNG CANCER IN HEAVY SMOKERS AND IN HEALTHY SUBJECTS

1 Jan 2007

Abstract excerpt

Abnormality in the fragile histidine triade (FHIT), a candidate tumor suppressor gene located in chromosome region 3 (3p14.2), has been frequently found in multiple tumor types, including lung cancer. In this study, the authors assessed the consistency of DNA microsatellite analysis of induced sputum (IS), as compared to that of blood and plasma. They also evaluated the loss of heterozigosity (LOH) and...

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PMID: 17694439
DOI: 10.1080/01902140701539687

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