Article
Plasma DNA microsatellite panel as sensitive and tumor-specific marker in lung cancer patients.
International journal of cancer - 20 Jun 2003
Beau-Faller Michèle, Gaub Marie Pierre, Schneider Anne, Ducrocq Xavier, Massard Gilbert, Gasser Bernard, Chenard Marie Pierre, Kessler Romain, Anker Philippe, Stroun Maurice, Weitzenblum Emmanuel, Pauli Gabrielle, Wihlm Jean Marie, Quoix Elisabeth, Oudet Pierre
Abstract excerpt
The majority of lung cancer patients have tumor-derived genetic alterations in circulating plasma DNA that could be exploited as a diagnostic tool. We used fluorescent microsatellite analysis to detect alterations in plasma and tumor DNA in 34 patients who underwent bronchoscopy for lung cancer, including 11 small cell lung cancer (SCLC) and 23 nonsmall cell lung cancer (NSCLC) (12 adenocarcinomas, 11 squamous...
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