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Article

Association of distinct allelic haplotypes of DISC1 with psychotic and bipolar spectrum disorders and with underlying cognitive impairments.

Human molecular genetics - 15 Oct 2007

Palo Outi M, Antila Mervi, Silander Kaisa, Hennah William, Kilpinen Helena, Soronen Pia, Tuulio-Henriksson Annamari, Kieseppä Tuula, Partonen Timo, Lönnqvist Jouko, Peltonen Leena, Paunio Tiina

Abstract excerpt

Bipolar disorder (BPD) and schizophrenia (SCZ) have at least a partially convergent aetiology and thus may share genetic susceptibility loci. Multiple lines of evidence emphasize the role of disrupted-in-schizophrenia-1 (DISC1) gene in psychotic disorders such as SCZ. We monitored the association...

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Source

Identifiers

PMID: 17673452
DOI: 10.1093/hmg/ddm207

Genes

DISC1
TSNAX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17673452-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Association of distinct allelic haplotypes of DISC1 with psychotic and bipolar spectrum disorders and with underlying cognitive impairments.PMID 17673452Read ↗

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Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder.Semantic proximity Read ↗

Sequencing of DISC1 pathway genes reveals increased burden of rare missense variants in schizophrenia patients from a northern Swedish population.Semantic proximity Read ↗

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