Article
Identification of polymorphisms within Disrupted in Schizophrenia 1 and Disrupted in Schizophrenia 2, and an investigation of their association with schizophrenia and bipolar affective disorder.
Psychiatric genetics - 1 Jun 2001
Devon R S, Anderson S, Teague P W, Burgess P, Kipari T M, Semple C A, Millar J K, Muir W J, Murray V, Pelosi A J, Blackwood D H, Porteous D J
Abstract excerpt
We have undertaken a search for polymorphic sequence variation within Disrupted in Schizophrenia 1 and Disrupted in Schizophrenia 2 (DISC1 and DISC2), which are both novel genes that span a translocation breakpoint strongly associated with schizophrenia and related psychoses in a large Scottish family. A scan of the coding sequence, intron/exon boundaries, and part of the 5' and 3' untranslated regions of DISC1,...
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