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Article

Intrinsic dynamic behavior of fascin in filopodia.

Molecular biology of the cell - 1 Oct 2007

Aratyn Yvonne S, Schaus Thomas E, Taylor Edwin W, Borisy Gary G

Abstract excerpt

Recent studies showed that the actin cross-linking protein, fascin, undergoes rapid cycling between filopodial filaments. Here, we used an experimental and computational approach to dissect features of fascin exchange and incorporation in filopodia. Using expression of phosphomimetic fascin mutants, we determined that fascin in the phosphorylated state is primarily freely diffusing, whereas actin bundling in...

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Identifiers

PMID: 17671164
DOI: 10.1091/mbc.e07-04-0346
PMCID: PMC1995713

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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