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Article

Fascin phosphorylation sites combine to regulate esophageal squamous cancer cell behavior.

Amino acids - 1 May 2017

Zeng Fa-Min, Wang Xiao-Ning, Shi Hong-Shun, Xie Jian-Jun, Du Ze-Peng, Liao Lian-Di, Nie Ping-Juan, Xu Li-Yan, Li En-Min

Abstract excerpt

Filopodia are dynamic membrane extensions generated by F-actin bundling and are involved in cancer cell migration, invasion and metastasis. Fascin is the crucial actin-bundling protein in filopodia, with phosphorylation at fascin serine 39 being well characterized to regulate fascin-mediated actin bundling in filopodia. However, increasing evidence indicates that fascin is phosphorylated at a number of sites....

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Identifiers

PMID: 28251354
DOI: 10.1007/s00726-017-2398-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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