Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Possible role of MDR1 two-locus genotypes for young-age onset ulcerative colitis but not Crohn's disease.

European journal of clinical pharmacology - 1 Oct 2007

Fiedler T, Büning C, Reuter W, Pitre G, Gentz E, Schmidt H H, Büttner J, Ockenga J, Gerloff T, Meisel C, Lochs H, Roots I, Köpke K, Johne A

Abstract excerpt

BACKGROUND: The role of the single nucleotide polymorphisms (SNPs) on positions 2677G>T/A and 3435C>T of the multi-drug-resistance gene 1 (MDR1) in inflammatory bowel disease (IBD) remains unclear. AIMS: To further elucidate the potential impact of MDR1 two-locus genotypes on susceptibility to IBD and disease behaviour. PATIENTS AND METHODS: Three hundred eighty-eight German IBD patients [244 with Crohn's disease...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Inflammatory Agents
Share to ATP Binding Cassette Transporter, Subfamily B

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ATP Binding Cassette Transporter, Subfamily B, Member 1

Share to Colitis, Ulcerative

Share to Crohn Disease

Share to Germany

Share to Glucocorticoids

Share to Severity of Illness Index

Source

Identifiers

PMID: 17665184
DOI: 10.1007/s00228-007-0334-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Possible role of MDR1 two-locus genotypes for young-age onset ulcerative colitis but not Crohn's disease.PMID 17665184Read ↗

Multidrug resistance 1 gene polymorphism and susceptibility to inflammatory bowel disease.Semantic proximity Read ↗

MDR1 polymorphisms are associated with inflammatory bowel disease in a cohort of Croatian IBD patients.Semantic proximity Read ↗

MDR1 gene: susceptibility in Spanish Crohn's disease and ulcerative colitis patients.Semantic proximity Read ↗

Genetic analysis of MDR1 and inflammatory bowel disease reveals protective effect of heterozygous variants for ulcerative colitis.Semantic proximity Read ↗

Multidrug resistance 1 gene in inflammatory bowel disease: a meta-analysis.Semantic proximity Read ↗

Allelic variations of the multidrug resistance gene determine susceptibility and disease behavior in ulcerative colitis.Semantic proximity Read ↗

Multidrug resistance 1 gene polymorphisms are not associated with inflammatory bowel disease and response to therapy in Italian patients.Semantic proximity Read ↗

MDR1 C3435T polymorphism is predictive of later onset of ulcerative colitis in Japanese.Semantic proximity Read ↗

Multidrug resistance 1 gene polymorphisms may determine Crohn's disease behavior in patients from Rio de Janeiro.Semantic proximity Read ↗

Absence of association between the multidrug resistance (MDR1) gene and inflammatory bowel disease.Semantic proximity Read ↗

Is there evidence to claim or deny association between variants of the multidrug resistance gene (MDR1 or ABCB1) and inflammatory bowel disease?Semantic proximity Read ↗

Associations between ABCB1/MDR1 gene polymorphisms and Crohn's disease: a gene-wide study in a pediatric population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.