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Article

Multidrug resistance 1 gene in inflammatory bowel disease: a meta-analysis.

World journal of gastroenterology - 21 Jun 2006

Annese V, Valvano M-R, Palmieri O, Latiano A, Bossa F, Andriulli A

Abstract excerpt

The MDR1 gene is an attractive candidate gene for the pathogenesis of inflammatory bowel disease (IBD) and perhaps response to therapy, with evidences at both functional and genetic levels. Its product, the P-glycoprotein (P-gp) functions as a transmembrane efflux pump thus influencing disposition and response of many drugs, some of whom (i.e. glucocorticoids) central to IBD therapy. In addition P-gp is highly...

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Share to ATP Binding Cassette Transporter, Subfamily B, Member 1
Share to Colitis, Ulcerative

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genes, MDR

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Source

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Identifiers

PMID: 16773678
DOI: 10.3748/wjg.v12.i23.3636
PMCID: PMC4087454

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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