Article
Multidrug resistance 1 gene polymorphism and susceptibility to inflammatory bowel disease.
Inflammatory bowel diseases - 1 May 2007
Ardizzone S, Maconi G, Bianchi V, Russo A, Colombo E, Cassinotti A, Penati C, Tenchini M L, Bianchi Porro G
Abstract excerpt
BACKGROUND: Several studies have evaluated the role of the multidrug resistance 1 gene (MDR1) polymorphism, which encodes the membrane-bound efflux transporter P-glycoprotein 170, in determining susceptibility to and disease behavior in inflammatory bowel disease (IBD), but with conflicting results. METHODS: A total of 211 patients with Crohn's disease (CD), 97 patients with ulcerative colitis (UC), and 212...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
