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Article

LRRK2 G2385R and R1628P mutations are associated with an increased risk of Parkinson's disease in the Malaysian population.

BioMed research international - 1 Jan 2014

Gopalai Aroma Agape, Lim Shen-Yang, Chua Jing Yi, Tey Shelisa, Lim Thien Thien, Mohamed Ibrahim Norlinah, Tan Ai Huey, Eow Gaik Bee, Abdul Aziz Zariah, Puvanarajah Santhi Datuk, Viswanathan Shanthi, Looi Irene, Lim Soo Kun, Tan Li Ping, Chong Yip Boon, Tan Chong Tin, Zhao Yi, Tan E K, Ahmad-Annuar Azlina

Abstract excerpt

The LRRK2 gene has been associated with both familial and sporadic forms of Parkinson's disease (PD). The G2019S variant is commonly found in North African Arab and Caucasian PD patients, but this locus is monomorphic in Asians. The G2385R and R1628P variants are associated with a higher risk of...

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Identifiers

PMID: 25243190
DOI: 10.1155/2014/867321
PMCID: PMC4163406

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25243190-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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