Article
Frequent allelic losses on the short arm of chromosome 1 and decreased expression of the p73 gene at 1p36.3 in squamous cell carcinoma of the oral cavity.
International journal of oncology - 1 Feb 2002
Araki Daisuke, Uzawa Katsuhiro, Watanabe Toshihide, Shiiba Masashi, Miyakawa Akihisa, Yokoe Hidetaka, Tanzawa Hideki
Abstract excerpt
Frequent loss of heterozygosity (LOH) on the short arm of chromosome 1 (1p) has been reported in a series of human malignancies. To investigate the possible existence of tumor suppressor locus (or loci), we examined 41 primary oral squamous cell carcinomas (OSCCs) for LOH using a panel of 15 poly...
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