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Article

DNA copy number variation and loss of heterozygosity in relation to recurrence of and survival from head and neck squamous cell carcinoma: a review.

Head & neck - 1 Oct 2008

Chen Yu, Chen Chu

Abstract excerpt

Genetic aberrations, such as DNA copy number variation (CNV) and loss of heterozygosity (LOH), have been implicated in head and neck squamous cell carcinoma (HNSCC) initiation and progression. This review examines CNV and LOH as predictors of HNSCC recurrence and mortality. We searched PubMed for relevant publications and compared and discussed results from the articles. Certain CNV and LOH events have...

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Share to Carcinoma, Squamous Cell
Share to DNA, Neoplasm
Share to Head and Neck Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Loss of Heterozygosity

Share to Neoplasm Recurrence, Local

Share to Neoplasm Staging

Share to Oligonucleotide Array Sequence Analysis

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Source

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Identifiers

PMID: 18642290
DOI: 10.1002/hed.20861
PMCID: PMC3220418

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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