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Article

Distinct regions of loss of heterozygosity on 22q in different sites of head and neck squamous cell carcinomas.

Medical science monitor : international medical journal of experimental and clinical research - 1 Mar 2002

dos Reis Patricia Pintor, Poli-Frederico Regina Célia, dos Santos Rodrigo Mattos, Nishimoto Ines Nobuko, Kowalski Luiz Paulo, Rogatto Silvia Regina

Abstract excerpt

BACKGROUND: Frequent loss of heterozygosity (LOH) has been reported in many types of cancer, including head and neck carcinomas. Somatic deletions involving specific chromosomal regions are strongly associated with inactivation of the allele of a tumor suppressor gene located within the deleted region. In most studies concerning LOH in head and neck squamous cell carcinomas (HNSCC) the different anatomical sites...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 11889455

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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